Lipid Coating
Structural Shape of Bicelle
Bicelle refers to a layered disk-like structure, resembling a pancake, in a two-dimensional arrangement of LNP. To create this structure, different types of long-chain and short-chain lipids are utilized.
Bicelle Coating
Due to the pancake-like, two-dimensional layered disk structure of Bicelles, it is advantageous for coating a plane surface compared to spherical-shaped LNPs.
When Bicelle-shaped LNPs come into contact with a surface,
they fuse together to form a coating.
Mechanism of Solvent Assisted Lipid Bilayer (SALB)
SALB, an abbreviation for Solvent Assisted Lipid Bilayer, is a technique used to create a flat lipid bilayer structure, similar to a floor. Lipids that were dissolved in an organic solvent become coated on the surface when they encounter a aqueous solution.
Through LUCA AICell’s SALB technology, coating can be achieved easily and rapidly, allowing for the fabrication of various lipid combinations on different surfaces.
Tae H, Park S, Kim SO, Avsar SY, Cho NJ
Selective Recognition of Phosphatidylinositol Phosphate Receptors by C-Terminal Tail of Mitotic Kinesin-like Protein 2 (MKlp2).
The Journal of Physical Chemistry B, 2022.
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Meker S, Halevi O, Chin H, Sut TN, Jackman JA, Tan EL, Potroz MG, Cho NJ
Inkjet-Printed Phospholipid Bilayers on Titanium Oxide Surfaces: Towards Functional Membrane Biointerfaces.
Membranes, 2022, 12 (4): 361
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Sut TN, Tan SW, Jeon WY, Yoon BK, Cho NJ, Jackman JA
Streamlined Fabrication of Hybrid Lipid Bilayer Membranes on Titanium Oxide Surfaces: A Comparison of One- and Two-Tail SAM ...
Nanomaterials, 2022, 12 (7): 1153.
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Tae, HyunHyuk; Yang, Chungmo; Cho, Nam-Joon
Artificial Cell Membrane Platforms by Solvent-Assisted Lipid Bilayer (SALB) Formation.
Accounts of Materials Research
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Hyeonjin Park, Sut TN, Ferhan AR, Yoon BK, Zhdanov VP, Cho NJ, and Jackman JA
pH-Modulated Nanoarchitectonics for Enhancement of Multivalency-Induced Vesicle Shape Deformation at Receptor-Presenting Lipid
Langmuir, 2023
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