LNP Tethering

LNP 관찰

LNP Tethering

LUCA AICell’s LNP tethering platform

LNP 테더링 플랫폼은 관찰하고자 하는 LNP를 바닥에 묶어서 그 LNP를 계속해서 관찰할 수 있게 도와주는 플랫폼입니다.
LNP가 오랫동안 안정되게 유지 되는지를 확인할 수도 있으며, 약물을 흘려주어 해당 약물에 LNP가 파괴되는지
여부 등을 현미경으로 쉽게 관찰할 수 있게 도와주는 플랫폼입니다.

Park S, Jackman JA, Xu XB, Weiss PS, Cho NJ

Micropatterned Viral Membrane Clusters for Antiviral Drug Evaluation

ACS Applied Materials & Interfaces 2019; 11 (15), 13984–13990.

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Park S, Yorulmaz Avsar S, Cornell B, Ferhan AR, Jeon WY, Chung M, Cho NJ

Probing the influence of tether density on tethered bilayer lipid membrane (tBLM)-peptide interactions

Applied Materials Today 2020; 100527.

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Park S, Jackman JA, Cho NJ

Comparing the Membrane-Interaction Profiles of Two Antiviral Peptides: Insights into Structure–Function Relationship

Langmuir 2019; 35, 30, 9934-9943.

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Kim AR, Ng WB, Bernt W, Cho NJ

Validation of Size Estimation of Nanoparticle Tracking Analysis on Polydisperse Macromolecule Assembly.

Scientific Reports 2019; 9, 2639.

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Kim AR, Bernt W, Cho NJ

Improved Size Determination by Nanoparticle Tracking Analysis: Influence of Recognition Radius.

Analytical Chemistry 2019; 91, 15, 9508-9515.

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