LNP Tethering

LNP tracking

  • R&D
  • LNP Tethering

LNP Tethering

LUCA AICell’s LNP tethering platform

The LNP Tethering Platform is a sophisticated platform that enables continuous observation of LNPs by tethering them to the substrate. It allows for monitoring the long-term stability of LNPs and facilitates easy microscopic observation to determine whether LNPs are being disrupted by the introduction of drugs or other substances.

Park S, Jackman JA, Xu XB, Weiss PS, Cho NJ

Micropatterned Viral Membrane Clusters for Antiviral Drug Evaluation

ACS Applied Materials & Interfaces 2019; 11 (15), 13984–13990.


Park S, Yorulmaz Avsar S, Cornell B, Ferhan AR, Jeon WY, Chung M, Cho NJ

Probing the influence of tether density on tethered bilayer lipid membrane (tBLM)-peptide interactions

Applied Materials Today 2020; 100527.


Park S, Jackman JA, Cho NJ

Comparing the Membrane-Interaction Profiles of Two Antiviral Peptides: Insights into Structure–Function Relationship

Langmuir 2019; 35, 30, 9934-9943.


Kim AR, Ng WB, Bernt W, Cho NJ

Validation of Size Estimation of Nanoparticle Tracking Analysis on Polydisperse Macromolecule Assembly.

Scientific Reports 2019; 9, 2639.


Kim AR, Bernt W, Cho NJ

Improved Size Determination by Nanoparticle Tracking Analysis: Influence of Recognition Radius.

Analytical Chemistry 2019; 91, 15, 9508-9515.