Lipid Coating
Structural Shape of Bicelle
Bicelle refers to a layered disk-like structure, resembling a pancake, in a two-dimensional arrangement of LNP. To create this structure, different types of long-chain and short-chain lipids are utilized.
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Bicelle Coating
Due to the pancake-like, two-dimensional layered disk structure of Bicelles, it is advantageous for coating a plane surface compared to spherical-shaped LNPs.
When Bicelle-shaped LNPs come into contact with a surface,
they fuse together to form a coating.
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Mechanism of Solvent Assisted Lipid Bilayer (SALB)
SALB, an abbreviation for Solvent Assisted Lipid Bilayer, is a technique used to create a flat lipid bilayer structure, similar to a floor. Lipids that were dissolved in an organic solvent become coated on the surface when they encounter a aqueous solution.
Through LUCA AICell’s SALB technology, coating can be achieved easily and rapidly, allowing for the fabrication of various lipid combinations on different surfaces.
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Tae H, Park S, Kim SO, Avsar SY, Cho NJ
Selective Recognition of Phosphatidylinositol Phosphate Receptors by C-Terminal Tail of Mitotic Kinesin-like Protein 2 (MKlp2).
The Journal of Physical Chemistry B, 2022.
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Meker S, Halevi O, Chin H, Sut TN, Jackman JA, Tan EL, Potroz MG, Cho NJ
Inkjet-Printed Phospholipid Bilayers on Titanium Oxide Surfaces: Towards Functional Membrane Biointerfaces.
Membranes, 2022, 12 (4): 361
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Sut TN, Tan SW, Jeon WY, Yoon BK, Cho NJ, Jackman JA
Streamlined Fabrication of Hybrid Lipid Bilayer Membranes on Titanium Oxide Surfaces: A Comparison of One- and Two-Tail SAM ...
Nanomaterials, 2022, 12 (7): 1153.
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Tae, HyunHyuk; Yang, Chungmo; Cho, Nam-Joon
Artificial Cell Membrane Platforms by Solvent-Assisted Lipid Bilayer (SALB) Formation.
Accounts of Materials Research
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Hyeonjin Park, Sut TN, Ferhan AR, Yoon BK, Zhdanov VP, Cho NJ, and Jackman JA
pH-Modulated Nanoarchitectonics for Enhancement of Multivalency-Induced Vesicle Shape Deformation at Receptor-Presenting Lipid
Langmuir, 2023
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